Here we take a closer look at the Promoter, which provides the building blocks of the metallothionein (MT) protein. The idea of this supplement is to boost MT function in a natural way, thus allowing the body to then detoxify (or chelate) itself naturally.
Introducing the Promoter
As the Promoter boosts MT function, allowing the body to detoxify naturally, it may also result in the 'self-correcting' of some of the other dysfunctions that are present based on MT abnormalities. Many ASD children use this supplement with anecdotal evidence of positive effects.
MT proteins are made up of 14 amino acids and zinc. Many Autism Spectrum Disorder (ASD) patients are unable to efficiently cleave dietary proteins into the individual amino acids needed for the MT synthesis. The Promoter formulation provides all 14 amino acids, in the proportion found in MT proteins. The large amounts of cysteine required for MT synthesis are provided in the form of oral glutathione (GSH) which breaks down in the gastrointestinal tract with minimal side effects.
The glutathione works with selenium (also found in the Promoter) to enhance:
- the delivery of zinc to the cells, and
- the sequestering of mercury and other heavy metals
Unfortunately, the Promoter may also deplete the body of essential minerals, especially zinc. Therefore, aggressive zinc loading must precede full scale MT Promotion therapy for best results.*
The primary ingredient in this supplement is glutathione; with each capsule containing 200mg of oral GSH.
Glutathione is a tripeptide, (i.e. a peptide consisting of three amino acids - cysteine, glutamic acid and glycine, joined together by peptide bonds) and is the most powerful naturally occurring antioxidant in human cells.
Glutathione is highly active in many organ systems and tissues, and is an essential cofactor for many enzymes. It has a critical role in protecting our cells from oxidative stress and maintaining the immune system. In normal health the body uses its enormous glutathione stores to detoxify and remove toxins (e.g. mercury) from the body.
Ingredients (per 350mg capsule):
- Glutathione - 200mg
- Selenium - 20mcg
- Serine - 27.4mg
- Lysine - 5.7mg
- Alanine - 16.8mg
- Glycine - 11.6mg
- Threonine - 8.6mg
- Proline - 7.0mg
- Aspartic Acid - 8.5mg
- Asparagine - 5.5mg
- Glutamic Acid - 12.0mg
- Methionine - 6.3mg
- Glutamine - 4.4mg
- Isoleucine - 4.0mg
- Valine - 2.2mg
- Microcrystalline cellulose used as filler
PLEASE NOTE: These doses are standard and can be adapted to suit your individual needs. The Promoter is also available in a 175mg and 87.5mg standard dosage. Because of the need of medical supervision, this formulation is presently available by prescription only.
* see Primer article for more information